Biota
BIOTA-FAPESP International Workshop on Metabolomics in the Context of Systems Biology (Feb 25 and 26/2010) Versão em português
The BIOTA-FAPESP International Workshop on Metabolomics in the Context of Systems Biology: a rational approach to search for lead molecules from nature will be presented at FAPESP's building on February 25 and 26, 2010.
PROGRAM
February 25
8h00 - Registration
08h40 - Open Ceremony
Symposium I: Metabolomics and Systems biology as a tool for new drugs discovery
9h00 - Systems Biology: a Gateway to Novel Discoveries - Robert Verpoorte, Leiden University, Holland
9h50 - Integration of Structure and Ligands Based Drug Design Approaches for the Discovery of Lead Compounds from Natural Products - Adriano Andricopulo, USP, São Carlos, SP
10h15 - Inhibition of Photophosphorylation and Electron Transport Chain in Thylakoids by Natural Products - Maria Fátima das G. Fernandes da Silva, UFSCAR, São Carlos, SP
10h40 - The Development of New Products from Brazilian Biodiversity - Emerson Queiroz, Laboratório Aché, São Paulo, SP
11h05 - Coffee Break
11h20 - MS-based Metabolomic Approaches Combined with Microflow-NMR Methods for the Search of Original Stress Induced Biomarkers in Plants - Jean-Luc Wolfender, Université de Genève
12h10 - Discussion
12h30 - Lunch Time (restaurants around FAPESP)
Symposium II: Plants and Associate Microorganisms as Potential source of New Biologically Active Molecules
14h00 - Systems Biology of Symbiotic Bacteria and the Search for New Biologically Active Molecules- Jon Clardy, Harvard Medical School, USA
14h50 - Exploring Microbial Interactions in Natural Products Research- Monica Talarico Puppo, USP, Ribeirão Preto, SP
15h15 - Search for Potential Antitumoral, Antioxidant, Anti-inflammatory, Antifungal, Antidiabetic, Acetylcholinesterase and Myeloperoxidase Inhibitory Natural Compounds from Cerrado and Atlantic Forest - Dulce Helena Siqueira Silva, UNESP, Araraquara, SP
15h40 - Coffee Break
16h00 - Footprinting of the ‘Final-fate Compounds’ in Systems Biology: Reading the Nature’s Message- Mario Palma, UNESP, Rio Claro, SP
16h25 - Molecular diversity among basal Angiosperms - Massuo Jorge Kato, USP, São Paulo, SP
16h50 - Cultured Cyanobacteria: A Promising Source for Novel Bioactive Natural Products - Jimmy Orjala, University of Illinois at Chicago, USA
17h40 - Discussion
February 26
Symposium III: New Advance Methodology for the Search Drug Discovery
9h00 - New Advance Methodology for the Search Drug Discovery- Arthur Edison, University of Florida, USA
9h50 - ESI-MS/MS Techniques and Applications for the Analysis of Natural Products- Norberto Peporine Lopes, USP, Ribeirão Preto,SP
10h15 - ISearch to be applied in enantioselective oxidation of secondary alcohols and bioreduction of ketones - Leandro Helgueira Andrade, USP, São Paulo, SP
10h40 - Novel application of 2D and 3D-similarity searches to assess compound selectivity among Cytochrome P450 2C9, 2D6 and 3A4 substrates - Carlos Alberto Montanari, USP, São Carlos, SP
11h05 - Coffee Break
11h30 - Innovative Strategies to Enhance Structural Diversity of Natural Products and Discovery of their New Uses - A. A. Leslie Gunatilaka, The University of Arizona, USA
12h20 - Discussion
12h40 - Lunch Time (restaurants around FAPESP)
Symposium IV: New Approach to Screening Biodiversity Source Materials and New Trends in Pharmacology and Toxicology to Select New Targets
14h00 - Taxol, Tubulin and Tumors: Challenges in the New Era of Cancer Therapeutics- Suzan Band Horwitz, Albert Einstein College of Medicine, USA
14h50 - Signaling through acetylcholine: multiple targets, phylogenetic conser- vation, and rich pharmacology- Newton G. Castro, UFRJ, Rio de Janeiro
15h20 - Decoding the Signaling Network in Malaria Parasites - Célia Regina Silva Garcia, USP, São Paulo, SP
15h50- Recent Studies of Natural Products Isolated from Brazilian Plants: Evaluation of Antigenotoxicity, Antimutagenicity and Antitumoral Assays - Christiane Pienna Soares, UNESP, Araraquara, SP
16h15 - Coffee break
16h30 - Novel Heparinomimetics with Potential Therapeutic Use in Cardiovascular and Inflammatory Disorders - Helena B. Nader, UNIFESP, SP
17h00 - Discussion
Close Remarks
17h30 - Vanderlan da Silva Bolzani, UNESP, Araraquara, SP
FAPESP: Rua Pio XI, 1500 – Alto da Lapa - São Paulo – SP
Parking suggestion: Taticar, R. Jorge Americano, 89
Information: (11) 3838-4006/3838-4216